Mercedes-Benz S-Class (W221)
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Mercedes-Benz S-Class (W221)

@mercedes_benz_s_class_w221

About

The sixth generation of the Mercedes-Benz S-Class, known for its luxury, advanced technology, and performance.

Introduction Year

2005

Discontinuation Year

2013

Category

sedan

Platform

Mercedes-Benz Modular Rear Architecture

Variants

15 variants of the Mercedes-Benz S-Class (W221)

S 65 AMG

S 65 AMG

@6000cc_v12_amg_sedan

The S 65 AMG debuted in 2006, featuring a 6.0L V12 twin-turbo engine that produces an impressive 621 hp. This variant emphasizes extreme performance and luxury, incorporating advanced technology and bespoke design elements, catering to the high-end market.

0 cars
sedan
4 doors
0 trims
Introduced: 2006 Discontinued: 2013
S 280

S 280

@s_280_d1d16b19_7805_406c_bf3f_d5e1446d7dcc

The S 280 was introduced in 2005 as part of the W221 generation. It features a 2.8L V6 engine producing 204 hp, paired with a 7-speed automatic transmission. This sedan variant offers luxury features typical of the S-Class line, including high-quality materials and advanced technology.

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sedan
4 doors
0 trims
Introduced: 2005 Discontinued: 2010
S 350

S 350

@s_350_78808bf2_39b2_4df4_81d7_6463317b0d87

The S 350 was introduced in 2005 and remained in production until 2013. It is equipped with a 3.5L V6 engine generating 272 hp, coupled with a 7-speed automatic transmission. This variant provides a blend of performance and luxury, featuring advanced safety systems and premium interior options.

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sedan
4 doors
0 trims
Introduced: 2005 Discontinued: 2013
S 400 Hybrid

S 400 Hybrid

@s_400_hybrid_177aa95f_ba19_4fad_8cfc_e2fce221fe97

The S 400 Hybrid was introduced in 2009 as part of the W221 generation. It features a 3.5L V6 engine combined with an electric motor to produce a total output of 295 hp. This sedan emphasizes fuel efficiency and reduced emissions while maintaining luxury and performance, making it a pioneering hybrid variant in the S-Class lineup.

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sedan
4 doors
0 trims
Introduced: 2009 Discontinued: 2013
S 500

S 500

@s_500_6b7da914_1a3c_4359_b4b6_cd696a0651f1

The S 500 debuted in 2005 and continued until 2013. It is powered by a 5.5L V8 engine producing 388 hp, with a 7-speed automatic transmission. This variant represents a high level of luxury and performance, equipped with advanced technology and high-end materials, catering to those seeking a top-tier experience.

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sedan
4 doors
0 trims
Introduced: 2005 Discontinued: 2013
S 600

S 600

@s_600_8da78f3a_66bc_48d7_9156_5b410b26d106

The S 600 was introduced in 2006 and features a 5.5L V12 engine producing 510 hp. This variant is equipped with a 5-speed automatic transmission and showcases the ultimate in luxury and performance, including advanced comfort features and high-end technological integrations. It serves as one of the flagship models in the S-Class lineup.

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sedan
4 doors
0 trims
Introduced: 2006 Discontinued: 2013
S 63 AMG

S 63 AMG

@s_63_amg

The S 63 AMG was introduced in 2006, powered by a 6.2L V8 engine that produces 518 hp. This high-performance variant includes AMG-specific enhancements, such as sport-tuned suspension and aggressive styling features, making it a standout model within the W221 lineup for enthusiasts.

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sedan
4 doors
0 trims
Introduced: 2006 Discontinued: 2013
S 300 BlueTEC

S 300 BlueTEC

@3000cc_diesel_blueTec_sedan

The S 300 BlueTEC was introduced in 2010, featuring a 3.0L V6 diesel engine producing 245 hp. It utilizes BlueTEC technology for reduced emissions and improved fuel efficiency. This variant combines luxury with environmental performance, catering to eco-conscious consumers within the premium sedan segment.

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sedan
4 doors
0 trims
Introduced: 2010 Discontinued: 2013
S 320 CDI

S 320 CDI

@s_320_cdi_2f948476_741e_4706_be9d_5443f8b3c4b9

The S 320 CDI was introduced in 2005 and features a 3.2L inline-6 diesel engine producing 224 hp. This variant is known for its fuel efficiency and torque, providing a comfortable ride with the luxury features associated with the S-Class, appealing particularly to markets favoring diesel engines.

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sedan
4 doors
0 trims
Introduced: 2005 Discontinued: 2013
S 350 CDI

S 350 CDI

@s_350_cdi

The S 350 CDI was introduced in 2005, equipped with a 3.0L V6 diesel engine that produces 265 hp. This variant balances performance and efficiency, providing a smooth driving experience with high torque output, along with luxurious interior appointments characteristic of the S-Class.

0 cars
sedan
4 doors
0 trims
Introduced: 2005 Discontinued: 2013
S 600

S 600

@5513cc_v12_sedan

The S 600 was launched in 2005 and continued until 2013. It is powered by a 5.5L V12 engine that produces 510 hp, paired with a 7-speed automatic transmission. This high-end variant showcases the pinnacle of luxury and performance in the S-Class lineup, featuring opulent interior materials and advanced technological features.

0 cars
sedan
4 doors
0 trims
Introduced: 2005 Discontinued: 2013
S 280

S 280

@s_280_c389b739_76af_4ec1_a633_1734acedc1eb

The S 280 was introduced in 2005 as part of the W221 generation. It features a 2.8L V6 engine producing 204 hp, paired with a 7-speed automatic transmission. This sedan variant offers a balance of luxury and performance, suitable for entry-level buyers in the S-Class range. It was discontinued in 2010.

0 cars
sedan
4 doors
0 trims
Introduced: 2005 Discontinued: 2010
S 350

S 350

@s_350_fef5bbe5_7632_4032_b9d2_55cdf87d8763

The S 350 was introduced in 2005 and continued until 2013. It features a 3.5L V6 engine producing 272 hp, combined with a 7-speed automatic transmission. This variant provides a refined driving experience with advanced technology and high-end amenities, appealing to luxury sedan enthusiasts.

0 cars
sedan
4 doors
0 trims
Introduced: 2005 Discontinued: 2013
S 400 Hybrid

S 400 Hybrid

@s_400_hybrid_e592fb9e_a5c8_449b_936e_49f1157cb2c7

The S 400 Hybrid was introduced in 2009 as part of the W221 generation. It features a 3.5L V6 engine combined with an electric motor, producing a total output of 295 hp. This variant emphasizes eco-friendliness without sacrificing luxury, equipped with advanced hybrid technology and luxurious interior features.

0 cars
sedan
4 doors
0 trims
Introduced: 2009 Discontinued: 2013
S 500

S 500

@s_500_69e677d4_b515_4dce_b278_d16973b7c89e

The S 500 was introduced in 2005 and ran until 2013. It features a 4.7L V8 engine producing 402 hp, coupled with a 7-speed automatic transmission. This flagship variant offers premium comfort, advanced technology, and superior performance, making it a top choice among luxury sedan buyers.

0 cars
sedan
4 doors
0 trims
Introduced: 2005 Discontinued: 2013